السبت، 26 يناير 2013


TOPOGRAPHICAL ANATOMY OF THE HEAD, NECK AND TRUNK
MUSCLES OF THE HEAD              
CRANIOFACIAL MUSCLES
origin from the bones of face
are inserted to the skin !
nerve supply – Facial n.
Epicranius m. – frontal belly, occipital belly (two parts are inserted to the galea aponeurotica)
Muscles of  eyelids: Orbicularis oculi
                               (Levator palpebrae superioris)
                               Corrugator supercilii
Muscles of  the nose: Procerus
                                   Nasalis
Muscles of  the mouth: Orbicularis oris                                      Buccinator
                                    Levator labii superioris alaequae nasi       Zygomaticus major
                                    Levator labii superioris                             Zygomaticus minor
                                    Levator anguli oris                                    Risorius
                                    Depressor anguli oris
                                    Depressor labii inferioris
                                    Mentalis
MASTICATORY MUSCLES
nerve supply – Trigeminal n. (Mandibular br.)
Masseter m.:   O: zygomatic arch
                       I: the angle of mandible – masseteric tuberosity
Temporalis m.:   O: tempral fossa
                           I:  coronoid process of mandible
Lateral pterygoid m.: O: lateral plate of pterygoid process
                                 I: the neck of the mandible
Medial pterygoid m.:  O: pterygoid fossa
                                 I:  the angle of the mandible – internal surface
MUSCLES OF THE NECK
Platysma m.: O: the skin over the clavicle
                       I: the skin along the body of mandible
N.S.:  Facial n.
Sternocleidomastoid m.
F: F and E of head
N.S.: XI. n.
Suprahyoid group of muscles:
Digastricus m.:    O: digastric fossa of mandible
                          I:  mastoid notch
             anterior belly (N.S. trigeminal n.)
             posterior belly (N.S. facial n.)

Stylohyoid m.
Mylohyoid m.: O: mylohyoid line of mandible (N.S. trigeminal n.)
Geniohyoid m.: O: the spine of the mandible (N.S. hypoglossal ansa)
Infrahyoid group:  N.S.: ansa cervicalis = hypoglossal ansa
Sternohyoid m.                                 Thyrohyoid m.
Sternothyroid m.                              Omohyoid m. O: scapula
Scaleni muscles
function: flection of cervical spine, elevation of 1st and 2nd ribs
Nerve supply: cervical spinal nerves
Scalenus anterior
O: C3-C6 vertebrae (trensverse processes)
I: the 1st rib (in front of the groove for the subclavian a.)
Scalenus medius
O: C2-C7 vertebrae (trensverse processes)
I: the 1st rib – (behind the groove for the subclavian a.)
Scalenus posterior
O: C4-C5 vertebrae (trensverse processes)
I: the 2nd rib
Fissura scalenorum – scalenic fissure – the gap between scalenus anterior and medius
Subclavian a. and brachial plexus traverse this space
                     !! subclavian v. is not contained in the scalenic fissure,
                                               it is located in front of   the scalenus anterior
MUSCLES OF THE THORAX
1. Intercostales externi muscles  - ventrocaudal direction, absent ventrally (ant.
intercostal membrane)
2. Intercostales interni muscles - dorsocaudal direction, absent dorsally (post.
intercostal membrane)
3. Intercostales intimi – like internal, but inserted internally to the costal groove
N. S. Intercostal nerves
Diaphragm: O:  sternal part – sternum - xiphoid process
                        costal part – lower six ribs
                        lumbar part – upper lumbar vertebrae
                  I: central tendon  of diaphragm
                                            – shows openings for the inf. v. cava, aorta, oesophagus
F: main muscle of respiration                                                                                            
 N.S. Phrenic n. (cervical plexus)

MUSCLES OF THE ABDOMEN
Muscles form anterolateral abdominal wall
Produce: F, E, and Rotation of trunk
N.S.: intercostal nerves
Obliquus externus abdominis
   O: lower  8 ribs
   I: iliac crest, pubic crest, linea alba
Inguinal ligament – lower free thickened margin of the aponeurosis of the obliquus externus
                                  abdominis  muscle
                                  stretched between the ant. sup. iliac spine and pubic tubercle
Obliquus internus abdominis :
   O: inguinal ligament, iliac crest, thoracolumbar fascia
    I: linea alba
Transversus abdominis:
     O: lower 6 ribs, thoracolumbar fascia, iliac crest, inguinal ligament
     I: linea alba
Rectus abdominis m.:
    O: xiphoid process, costal cartillages
     I: pubic bone
N. S. of the muscles of the abdomen - lower six intercostal nerves
The rectus sheath:
- is formed by the aponeuroses of  obliquus ext, int. and transversus abdominis m.
- is composed of anterior and posterior layers above the level of the umbilicus
                           anterior layer below the level of umbilicus
INGUINAL CANAL
narrow canal in the anterior abdominal wall, immediately above the inguinal ligament
- directed mediocaudally
- traversed by  - spermatic cord in male
                        - round ligament of the uterus in female
           and ilioinguinal n.
Walls:
inferior wall: inguinal ligament
ventral wall: aponeurosis of the obliquus externus abdominis m.
superior wall: muscle  fibres of obliquus abdominis iternus and transversus abdominis
                                                                                                                                   muscles
dorsal wall: transverse fascia  - this is a very thin, weak wall!!
Opens
internally – deep inguinal ring – an aperture  in the transverse fascia
                                                                          inferior epigastric vessels lie near this opening
extenally – superficial inguinal ring – opening  in the aponeurosis of obliquus ext. abd. m

AORTA – ascending, aortic arch, descending aorta (thoracic, abdominal)
ASCENDING AORTA – coronary arteries
AORTIC ARCH
1. brachiocephalic a. -  right common carotid a.
                                     -  right subclavian a.
2. left common carotid a.
3. left subclavian a.
COMMON CAROTID ARTERY – external carotid, internal carotid
EXTERNAL CAROTID ARTERY
supplies -  the structures  on the neck and face,
              - the oral and nasal cavities (palate, teeth, tongue, paranasal sinuses)
             - superf. structures of the cranium
1. Superior thyroid a. – gives superior laryngeal a.
2. Lingual a.
3. Facial a. - submental a.
                  -  superior and inferior labial a.
                  - nasal and angular a.
4. Ascending pharyngeal a.
5. Occipital a.
6. Posterior auricular a.
7. Temporal superficial a.
                            - transverse facial a.
                            - frontal and parietal branches
8. Maxillary a.
     supplies the  mandible and  lower teeth, the maxilla and upper teeth, the nasal cavity and
     paranasal sinuses,the  masticatory muscles, middle meningeal a.
    - infraorbital a., mental a.
INTERNAL CAROTID ARTERY
Supplies the brain and some organs of senses
VEINS OF THE HEAD AND NECK      
External jugular v.  - opens into the internal jugular v.
           receives tributaries: occipital and posterior auricular veins
Internal jugular vein opens into the brachiocephalic v.
receives tributaries:
- sinus of dura mater (draining brain and organs of senses)
- superior thyroid v.
- lingual v.
- facial v.
- pharyngeal v.
- retromandibular v.
              maxillary vein (pterygoid plexus) and  temporal superficial v

SUBCLAVIAN ARTERY
1. Vertebral a. (brain)
2. Internal thoracic (mammary) a. supplies anterior thoracic and abdominal walls, anterior
                                                 mediastinum and diaphragm
                    - Mediastinal br., Pericardial br.
                    - Anterior intercostal br. – perforating branches
                    - Musculophrenic a.
    terminates as Superior epigastric a.
3. Thyreocervical trunk supplies organs and muscles of neck and back
    -  Inferior thyroid a. (gives laryngeal and pharyngeal branches)
    -  Ascending cervical
    -  Superficial cervical a.
4. Costocervical trunk  supplies the  skin and the muscles on the neck and the back
    - Deep cervical a.
    - Dorsal scapular a.
    - Superior intercostal a.
accompanying veins open into the brachiocephalic vein!!
SUBCLAVIAN VEIN
except axillary vein receives no important tributaries from the neck
                       Most the veins accompanying branches of subclavian  artery empty into the brachiocephalic
vein
BRACHIOCEPHALIC VEIN
Subclavian and Internal jugular veins join to form brachiocephalic v.
tributaries:
- Vertebral v.
- Internal thoracic v.
- Inferior thyroid v.
THORACIC AORTA
Supplies thoracic walls and organs (except ant. wall and heart)
- Intercostal arteries
- Superior phrenic arteries
- Oesophageal branches
- Bronchial arteries
blood is drained into  the  Azygos and Hemiazygos veins. Hemiazygos v. opens into the
Azygos v. and this terminates in the Superior vena cava.
SUPERIOR VENA CAVA
arises by union of brachiocephalic veins
azygos vein opens into the Sup. v. cava

ABDOMINAL AORTA
branches for the abdominal walls:
- Inferior phrenic arteries
- Lumbar arteries
branches for abdominal organs
- Suprerenal arteries
- Renal arteries
- Gonadal arteries – testicular/ovarian
- Coeliac artery -  splenic
                            -  left gastric
                            - common hepatic
- Superior mesenteric a. - supplies small intestine and large intestine – coecum, ascending
                                         and transverse colon near to the left colic flexure
-  Inferior mesenteric a.  -  supplies large intestine – left colic flexure, descending and
sigomod colon, upper part of rectum – superior rectal a.
the blood  from the abdominal wall and organs is drained into the Inferior vena cava
INFERIOR VENA CAVA
receives tributaries:
- Lumbar and Phrenic veins (from the walls)
- Suprarenal
- Renal and
- Testicular/Ovarian veins (from the paired organs)
- Hepatal veins – empty the blood from the liver ( which is carried into the liver by portal
                vein  draining  the blood from the spleen and digestive abdominal organs via
                        splenic v., gastric, superior and inferior mesenteric veins)                                              
                                               
COMMON ILIAC A.
EXTERNAL ILIAC A.
- Inferior epigastric a.
INTERNAL ILIAC A.
supplies the walls and the organs of the pelvis
- Superior gluteal a.
- Inferior gluteal a.
- Obturator a.
- Superior and Inferior vesical arteries
- Middle rectal a.
- Uterine a./A. of defferent duct
- Internal pudendal a.  – gives: inferior rectal a. and branches for supply of external genital
                                                organs
Blood from the pelvic walls and organs is drained into the accompanying veins

CERVICAL PLEXUS
arises by union of  ventral branches of C1 – C4 spinal nerves  
sensory nerves
1. Lesser occipital n.
2. Greater auricular n. – anterior and posterior branches
3. Transverse n. of neck
4. Supraclavicular nerves – medial, intermediate and lateral groups (upper part of thorax)
motor nerves
5. Phrenic n. (diaphragm)
6. Inferior root of the ansa cervicalis (nerve supply of infrahyoid muscles)

REGIONS OF THE HEAD
CRANIUM:
frontal region
parietal region
temporal region
occipital region
FACE:
nasal                  orbital
oral                    infraorbital and zygomatic
mental                buccal (here - parotideomasseteric)
REGIONS OF THE NECK
Boundaries: cranially – mandible…mastoid process…external occipital protuberance
                    caudally – jugular notch…clavicle…acromion…7th cervical vertebra spine
ANTERIOR NECK REGION   - between sternocleidomastoid muscles
      submental triangle
      digastric (submandibular) triangle
      carotid triangle
      laryngeal region
STERNOCLEIDOMASTOID REGION
LATERAL NECK REGION  between sternocleidomastoid m. and trapezius m.
      omoclavicular triangle  = greater supraclavicular fossa
      suprascapular region
POSTERIOR NECK REGION  overlying trapezii muscles
REGIONS OF THE THORAX:
presternal reg.
infraclavicular reg. and clavipectoral triangle
pectoral reg. – mammary and inframammary reg.
axillary reg.
REGIONS OF THE ABDOMEN
epigastric and right/lerft hypochondriac regions
umbilical and right/left lateral abdominal regions
pubic and right/left inguinal regions
REGIONS OF THE BACK
vertebral and sacral regions
scapular and infrascapular regions
lumbar regions

CRANIUM AND FACE
Frontal region
- supratrochlear vessels and nerve  (ophthalmic a. [I.C.A], ophthalmic n. [trigeminal])
- supraorbital vessels and nerve (ophthalmic a., ophthalmic n.)
- frontal branch of superficial temporal vessels
Temporal region
- temporal superficial vessels and their parietal branches
- auriculotemporal n. (sensory branch of trigeminal/mandibular)
- temporal branches of facial n. (motor)
-  middle and deep temporal vessels (branches from the maxillary a.)
- deep temporal n. (motor branch of trigeminal/mandibular)
Buccal region – parotideomasseteric
- parotid gland and parotid duct
- transverse facial vessels
- facial n. – temporal br.
               - zygomatic br.  
               - buccal br.
               - marginal  of mandible br.
- temporal superficial a. and v.
- auriculotemporal n.
- on deep surface of parotid gland - retromandibular v.
                                                     - external carotid a.
  - internal jugular v.
- greater auricular n. – anterior branch
Nasal, oral and infraorbital regions
- facial a. and v. and their branches
- inferior labial
- superior labial
- lateral nasal
- angular
- infraorbital a., v., n. (branches of maxillary a., v., n.)
Mental region
- mental a., v. and n. (sensory branch of trigeminal/mandibular)
THE NECK
SUPERFICIAL STRUCTURES
- external jugular v.
- anterior jugular v.
- lesser  occipital n.
- greater auricular n.
- transverse n. of the neck
- supraclavicular nerves – medial, intermediate, lateral

DEEP STRUCTURES
Carotid triangle:
borders: sternocleidomastoid m.
              omohyoid m. – superior belly
              digastricus m. – posterior belly
content:
-  common carotid a.
        - external carotid a. (and its branches – sup. thyroid, facial, lingual)
        - internal carotid a.
- internal jugular v.  (and its tributaries . sup. thyroid, facial, lingual)
- vagus n.
- hypoglossal n.
- hypoglossal ansa (superior and inferior roots)
- cervical sympathetic trunk
- deep lymph. nodes of the neck
Digastric triangle – submandibular triangle
borders: mandible
              digastricus and stylohyoid muscles
content:
- submandibular gland
- facial v.
- facial a. (deeply than vein)
- hypoglossal n.
- submandibular lymph nodes
Laryngeal region
- thyroid gland
- superior thyroid a. and v.
- inferior thyroid a. and v.
                           
Lateral neck region
- subclavian a. and v.
- superficial cervical a. and v.
- transverse cervical a. and v.
- brachial plexus      
- accessory n.
THORAX
anterior and lateral thoracic regions
superficial structures: – vessels and nerves for supplying the skin and subcutaneous tissues
- supraclavicular nerves
- anterior cutaneous branches of intercostal vessels and nerves, and their mammary branches
- lateral cutaneous branches of intercostal vessels and nerves
- perforating rami of internal thoracic vessels, and their mammary branches
- mammary gland

deep structures:
- muscles – pectoralis major and minor,  serratus anterior, intercostal muscles
- thoracoepigastric vein
- lateral thoracic a. and v.
- long thoracic n.
- internal thoracic a. and v.
- intercostal arteries, veins and nerves
ABDOMEN
superficial structures
- thoracoepigastric vein
- superficial epigastric vessels
- circumflex ilium superficial vessels
- anterior and lateral cutaneous branches of intercostal vessels and nerves
deep structures
muscles: rectus abdominis m. and its sheath
                   superior and inferior epigastric vessels on its inner surface
              obliquus externus abdominis m.
              obliquus internus abdominis m.
              transversus abdominis m.










Abdomen: Topographic Anatomy
    Abdomen: General description
  • Lies between the diaphragm and the pelvic inlet.
  • Is the largest cavity in the body and is continuous with the pelvic cavity.
  • Lined with parietal peritoneum, a serous membrane
  • Bounded superiorly by the diaphragm
    • Has a concave dome
    • Spleen, liver, part of the stomach, and part of the kidneys lies under the dome and are protected by the lower ribs and costal cartilages.
  • Lower extent lies in the greater pelvis
    • Between the ala or wings of the ilia
    • Ileum, cecum, and sigmoid colon thus partly protected
  • Anterior and lateral walls composed of muscle
    • Viscera in these areas are more likely to be damaged by blunt force and penetrating injuries.
  • Posterior wall comprised of vertebral column, the lower ribs, and associated muscles
    • Protect the abdominal contents.
    Bony landmarks of the abdomen 
  • Xiphoid process
  • Lower six costal cartilages
  • Anterior ends of the lower six ribs (ribs 7 to 12) (Section 3-3: ThoraxBody Wall)
  • Lumbar vertebrae (L1 to L5)
  • Pelvis
    • Iliac crest
    • Anterior superior iliac spine (ASIS)
    • Anterior inferior iliac spine
    • Pubic symphysis
    • Pubic crest and pubic tubercle
    Abdomen: Topographical anatomy 
  • Costal margin: Formed by the medial borders of the 7th through 10th costal cartilages
  • Rectus sheath
    • From xiphoid process and 5th through 7th costal cartilages → pubic symphysis and pubic crest
    • Contains rectus abdominis muscle (Section 4-2: AbdomenBody Wall)
  • Linea alba
    • A slight indentation that can sometimes be seen extending from the xiphoid process to the pubic symphysis
    • A fibrous raphe where the aponeuroses of the external and internal abdominal oblique and the transversus abdominis muscles on either side unite.
  • Semilunar line (linea semilunaris)
    • Vertical indentation seen as a curved line from the tip of the ninth rib cartilage to the pubic tubercle on each side in well-muscled individuals
    • Represents the lateral edge of the rectus abdominus muscle
  • Tendinous intersections
    • Transverse attachments between the anterior rectus sheath and rectus abdominis muscle
    • May be seen as transverse grooves in skin on either side of midline (six-pack)
  • Inguinal ligament
    • From ASIS to pubic tubercle of pelvis
    • Folded inferior edge of external abdominal aponeurosis
    • Separates abdominal region from thigh
  • Umbilicus
    • At approximate level of intervertebral disc between the L3 and L4
    • Marks the T10 dermatome
  • Liver 
    • Mainly in the right upper quadrant, behind ribs 7 through 11 on the right side
    • Crosses the midline to reach towards the left nipple (Section 4-5: AbdomenViscera (Accessory Organs))
  • Spleen
    • Beneath ribs 9 through 11 on the left side
    • 10th rib is axis of spleen
  • Kidneys
    • Located in loin region
    • Left kidney is higher than right (pelvis at L1/2 on left and L2/3 on right) (Section 4-8: AbdomenKidneys and Suprarenal Glands)

    Abdominal contents 
  • Gastrointestinal tract
    • Stomach
    • Duodenum
    • Ileum
    • Jejunum
    • Cecum and appendix
    • Ascending, transverse and descending colon
    • Part of the sigmoid colon
  • Accessory digestive organs
    • Liver
    • Gallbladder
    • Pancreas
  • Spleen
  • Suprarenal glands
  • Urinary system—kidneys and ureters
    • Kidneys are the only organs developing beneath the parietal peritoneum
    • Never have a mesentery
    • Thus are primarily retroperitoneal
  • Organs that develop within the abdominal cavity and then become retroperitoneal
    • Are called secondarily retroperitoneal
    • Pancreas
    • Two thirds of the duodenum
    • Ascending and descending colon.
  • All the rest of the organs are peritoneal
    • Lie within the peritoneal cavity
    • Covered by a layer of visceral peritoneum
    • Visceral peritoneum is continuous with the parietal peritoneum lining the cavity via a mesentery


Name of muscle
(nerve supply)
OriginInsertionAction
External oblique
(T5-T12 spinal nerves)
External surface of ribs 5-12Becomes aponeurotic and attaches to the xiphoid process, linea alba, pubic crest, pubic tubercle, and anterior half of iliac crestFixes and rotates trunk, pulls down ribs in forced expiration
Internal oblique (spinal nerves T6-T12, iliohypogastric and ilioinguinal nerves)Thoracolumbar fascia anterior two-thirds of iliac crest, lateral half of inguinal ligamentInferior border of ribs 10-12 and their costal cartilages, pubic crest and pectin pubis via conjoint tendon with transversusAssists in flexing and rotating trunk; pulls down ribs in forced expiration
Transversus abdominis (spinal nerves T5-T12, iliohypogastric and ilioinguinal nerves)Internal surface of lower six costal cartilages, thoracolumbar fascia, iliac crest, lateral third of inguinal liagementPubic crest, linea alba, symphysis pubis; forms conjoint tendon to pectus pubis with internal obliqueCompresses and supports abdominal contents and flexes external and internal oblique muscles
Rectus abdominis (spinal nerves T6-T12)Symphysis pubis and pubic crestCostal cartilages 5-7 and xiphoid processCompresses abdominal contents and flexes trunk (lumbar vertebrae)

    Abdominal regions 
  • Abdominal quadrants
    • Clinicians usually divide the abdomen is into four quadrants for descriptive purposes, using the following planes:
      • Median plane: imaginary vertical line following the line alba from the xiphoid process to the pubic symphysis
      • Transumbilical plane: imaginary horizontal line at the level of the umbilicus
    • These lines or planes create four quadrants 
      • Right upper
      • Left upper
      • Right lower
      • Left lower
  • Abdominal regions
    • Clinicians may divide the abdomen into nine regions
      • For more accurate descriptive and diagnostic purposes
      • Use two vertical and three horizontal lines or planes
    • Horizontal planes (in descending order):
      • Subcostal plane: passes through the lower border of the 10th costal cartilage on either side
      • Sometimes the transpyloric plane is used instead of the subcostal; passes through the pylorus on the right and the tips of the ninth costal cartilage on either side)
      • Transumbilical plane: passes through the umbilicus at the level of the L3/4 intervertebral disc
      • Transtubercular (intertubercular) plane: passes through the tubercles of the iliac crests and the body of L5
    • Vertical planes
      • Right midclavicular line
      • Left midclavicular line
      • Pass from the midpoint of the clavicle to the midpoint of inguinal ligament.
    • These planes create nine abdominal regions: 
      • Right and left hypochondriac regions, superiorly on either side
      • Right and left lumbar (flank) regions, centrally on either side
      • Right and left inguinal (groin) regions, inferiorly on either side
      • Epigastric region superiorly and centrally
      • Umbilical region, with the umbilicus as its center
      • Hypogastric or suprapubic region, inferiorly and centrally
  • Descriptive quadrants and regions are essential in clinical practice
    • Each area represents certain visceral structures
    • Allow correlation of pain and referred pain from these areas to specific organs.
  • Regions and quadrants are palpated, percussed, and auscultated during clinical examination




RIGHT UPPER QUADRANT (RUQ)LEFT UPPER QUADRANT (LUQ)
 •  Liver (right lobe)
 •  Gallbladder
 •  Pylorus (of stomach)
 •  Duodenum (parts 1 through 3)
 •  Pancreas (head)
 •  Right kidney and suprarenal gland
 •  Colon: distal ascending colon, hepatic flexure and right half of transverse colon
 •  Liver (left lobe)
 •  Spleen
 •  Stomach
 •  Jejunum and proximal ileum
 •  Pancreas (body and tail)
 •  Left kidney and suprarenal gland
 •  Colon: left half of transverse colon, splenic flexure and superior part of descending colon
RIGHT LOWER QUADRANT (RLQ)LEFT LOWER QUADRANT (LLQ)
 •  Majority of ileum
 •  Cecum with vermiform appendix
 •  Proximal ascending colon
 •  Proximal right ureter
 •  Distal descending colon
 •  Sigmoid colon
 •  Left ureter
 •  Ovaries
 •  Uterine tubes
 •  Right and left ductus deferens
 •  Uterus (if enlarged)
 •  Urinary bladder (if full, especially in women)


الجمعة، 25 يناير 2013



The preoperative visit usually involves the following actions:
  • Review of medical history, family history and social habits
  • Physical examination
  • Request for additional examinations
  • Risk assessment
  • Explanation of the GA procedure and risks
  • Informed consent form
  • GA procedure planning
  • Prescription of premedication
  • Pre-operative instructions
The first step of the pre-anesthetic evaluation is the review of the patient’s medical history (health conditions and medications), family history, and social history.
Medical History
Reviewing of the past medical history of the patient is an essential part of the preparation for general anesthesia. Your dentist anesthesiologist needs to know about your past and present health conditions.
The existence of diseases such as asthma, diabetes, tuberculosis, seizures or any chronic major organ dysfunction, but particularly diseases of the cardiovascular and respiratory systems, is a significant factor in deciding if a patient is a suitable candidate for general anesthesia, or which anesthetic drugs should be used.
Identification of pregnancy in the first trimester is a contraindication to GA due to the risk of teratogenicity. Pregnant women are generally at a higher risk of regurgitation and aspiration of gastric contents during general anesthesia. It is also generally agreed that the elderly are subject to increased risks of anesthesia.
Previous anesthesia history - Adverse reactions to anesthesia
Your dentist or anesthesiologist must be notified if you (or any other member of your family) have a history of problems or adverse reactions to general anesthesia, such as allergic reactions, intubation problems, anesthesia awareness during GA, or postoperative nausea and vomiting. Several related problems are caused by hereditary disorders which need special attention.
Medications usage
Several common medications may interact with anesthesia drugs either enhancing or reducing their effect. Failure to fully disclose medication usage can increase the risks associated to general anesthesia, because many drug interactions can be potentially dangerous.
Provide the dentist anesthesiologist with a full list of all the medications you take regularly (both prescription and over-the-counter medications), and any other medication you may have taken in the last days. Do not forget to include in the list and any herbal products, natural supplements or alternative medicines you take, because some of them (e.g. valerian, and ginseng) can also interact with certain general anesthesia drugs. Your dentist must also know about any allergic reactions you've had to medicines in the past.
The anesthesiologist will advise you if you have to adjust the dosage or suspend taking certain medications prior or after the general anesthesia procedure.
Family history – Hereditary problems
Some hereditary conditions can cause dangerous complications during general anesthesia, if the anesthesiologist is not made aware of them. Family medical history is useful in identifying possible hereditary conditions such as:
  • Malignant hyperthermia. Malignant hyperthermia (MH) is an inherited disorder with a high mortality rate, which may occur during GA causing uncontrolled rise of body temperature.
  • Porphyria. A rare hereditary blood disorder in which the hemoglobin is abnormally metabolized, resulting in excessive production of porphyrins. The condition may be triggered by some drugs used in GA such as barbiturates.
  • Suxamethonium apnea. It is a rare condition where the patient’s body metabolizes very slowly the drug suxamethonium (succinylcholine) which is used in general anesthesia procedures as a muscle relaxant. As a result the patient may remain paralyzed and unable to breath for longer periods, requiring ventilation support.
Social history and habits (smoking, alcohol, drug usage)
Patients with social habits such as smoking, alcohol or drug usage are more susceptible to complications during or after GA. Any such usage must be disclosed to the dentist anesthesiologist in order to adjust accordingly the anesthesia planning (drug selection and dosage), or suggest another alternative solution.
  • Smoking. Smoking has negative effects on the respiratory tract and function, reducing the oxygen-carrying capacity of the blood, and increasing the incidence of respiratory infection and postoperative respiratory morbidity. Patients should stop smoking for at least 12 hours before anesthesia (ideally they should stop smoking for 6 weeks before anesthesia) to reduce this risk.
  • Alcohol. Regular consumption of alcohol may have caused liver damage affecting the metabolism and lead to tolerance to anesthetic drugs.
  • Drug abuse. Except of the obvious problem due to drug interactions, other issues for general anesthesia in drug abusers include possible inadequate venous access and increased risk for existence of infectious diseases such as HIV or hepatitis. Drug and alcohol abusers are at a much higher risk of anesthesia awareness.
Physical examination
A full physical examination is important to complement the preanesthetic evaluation. The dentist anesthesiologist will particularly focus on the patient's airway, inspecting the mouth and pharynx soft tissues, and neck’s flexibility. The patient will also be checked for loose teeth, dentures, or crowns.
The vital signs of the patient (e.g. blood pressure, heart rate, oxygen saturation) will be checked and recorded. A more extensive physical examination may be required for medically compromised patients.
Request for additional examinations
Although healthy patients under 40 years old may not require further preanesthetic examinations, a blood and urine test, and a chest x-ray are typically recommended. These tests can reveal conditions related to the lung, heart, liver, or kidney function, diabetes or other problems that the patient may be unaware of.
Additional examinations may be asked for patients with a history of health conditions, in order to determine their exact health status.

LOCAL COMPLICATIONS OF ANAESTHETICS

A)COMPLICATIONS ARISING FROM DRUGS OR CHEMICAL USED
1.SOFT TISSUE INJURY
2.SLOUGHING OF TISSUES

B)COMPLICATIONS ARISING FROM INJECTION TECHNIQUES
1)NEEDLE BREAKAGE
2)HEMATOMA
3)FAILURE TO OBTAIN LOCAL ANESTHESIA
4)POST-INJECTION HERPETIC LESIONS

C)COMPLICATIONS ARISING FROM BOTH
1)PAIN ON INJECTION
2)BURNING ON INJECTION
3)TRISMUS
4)BLANCHING OF SKIN
5)EDEMA
6)PERSISTENT PARATHESIA OR ANESTHESIA
7)INFECTION
8)PERSISTENT PAIN
9)NEUROLOGICAL SYMPTOMS
               FACIAL N. PARALYSIS
               VISUAL DISTURBANCES


1)SOFT TISSUE INJURY


CAUSES
PREVENTION
MANAGEMENT
-SELF INFLICTED TRAUMA TO LIPS ,TONGUE WHILE STILL NUMB
-SEEN IN CHILDREN AND MENTALLY AND PHYSICALLY DISABLED
-SOFT TISSUE ANESTHESIA LASTS LONGER THEN PULPAL
-APPROPRIATE DURATION LA
-COTTON ROLLS BETWEEN LIPS AND TEETH
-WARN THE PATIENT AND GUARDIAN AGAINST EATING,DRINKING HOT FLUIDS AND BITING ON LIPS OR TONGUE TO TEST FOR ANESTHESIA
-ANALGESICS FOR PAIN
-ANTIBIOTICS
-LUKEWARM SALINE RINSES TO AID IN DECREASE ANY SWELLING THAT MAY BE PRESENT
-PETROLEUM JELLY AS LUBRICANT
2)SLOUGHING OF TISSUES


i)EPITHELIAL DEQUAMATION
-TOPICAL ANESTHETIC FOR PROLONGED PERIOD
-HIGHTENED SENSTIVITY OF TISSUE TO LA REACTION IN AREA OF TOPICAL ANESTHETICS
ii)STERILE ABSCESS
-PROLONGED --ISCHEMIA DUE TO VASOCONSTRICTOR
-DEVELOPS ON HARD PALATE
-DO NOT USE HIGH CONC. LA WITH VASOCONSTRICTOR
(NOREPINEPHRINE 1:30,000 NOT PRESCRIBED)
DEPEND ON INJURY
-SYMPTOMATIC-ANALGESICS,ORABASE
-RESOLVES WITHIN 1-2 WEEKS
-AN ESTABLISH LESION MAY REQUIRE INCISION AND DRAINAGE



B)COMPLICATIONS ARISING FROM INJECTION TECHNIQUES

1)NEEDLE BREAKAGE

CAUSES

PRIMARY CAUSE-
              UNEXPECTED MOVEMENT OF PATIENT
SECONDARY CAUSE-
¤  INAAPROPRIATE THICKNESS OF NEEDLE
¤  PREVIOUSLY BENT
¤  REDIRECTION OF NEEDLES ONCE INSERTED INSIDE TISSUE
¤  MANUFACTURE DEFECT(RARE)
¤  FORCING NEEDLE AGAINST RESISTENCE
¤  NEEDLE ENGAING THE PERIOSTEUM


PREVENTION
v  INFORM THE PATIENT
v  USE PROPER GAUZE NEEDLE(FOR N. BLOCK-25 GAUZE,FOR INFILTRATION-27,25,30 GAUZE
v  USE PRESTERLIZED DISPOSABLE NEEDLES
v  ENTIRE LENGTH SHOULD NOT BE INSERTED(FEW MM AWAY FROM HUB)
v  DO NOT REDIRECT IF EMBEDDED
v  USE GOOD QUALITY NEEDLE
v  GENTLE MANIPULATION-NO EXCESSIVE FORCE
v  DO NOT PERMIT THE NEEDLE TO ENGAGE THE PERIOSTEUM
v  STABILISATION OF JAW
v  NEEDLE SHOULD ALWAYS BE KEPT DURING INSERTION
v  AVOID MULTIPLE PENETRATIONS

MANAGEMENT
CALM,DO NOT PANIC
INFORM PATIENT
IF VISIBLE-USE HEMOSTAT OR MAC GILLS TUBE
IF NOT-FLOUROSCOPE,FOLLOW UP,SURGERY



2)HEMATOMA

THE EFFUSION OF BLOOD INTO EXTRAVASCULAR SPACES CAN RESULT FROM INADVERTENTLY NICKING A BLOOD VESEL(ARTERY OR VEIN)DURING THE INJECTION OF LA

NICKING OF ARTERY-HEMATOMA INCRESE RAPIDLY IN SIZE
NICKING OF VEIN-MAY OR MAY NOT RESULT IN FORMATION

CAUSE
NICK→BLOOD EFFUSES FROM VESSELS UNTIL EXTRAVASCULAR PRESURRE EXCEEDS INTRAVASCULAR→CLOTTING OCCURS

PREVENTION
³  MODIFY INJECTION TECHNIQUE AS DICTATED BY PATIENT
³  USE SHORT NEEDLE(APPROPRIATE LENGTH)
³  MINIMIZE NO. OF PENETRATION
³  NEVER USE NEEDLE AS A PROBE ON TISSUE

MANAGEMENT

IMMEDIATE-DIRECT PRESSURE AT SITE OF BLEEDING FOR NOT LESS THAN 2 MINS
BLOCK
PRESSURE SITE
CLINICAL MANIFESTATION
IANB
MEDIAL ASPECT OF MANDIBULAR RAMUS
INTRAORAL DISCOLORATION AND PROBABLE TISSUE SWELLING ON MEDIAL ASPECT OF MANDIBULAR RAMUS

INFRAORBITAL
INFRAORBITAL FORAMEN
DISCOLORATION OF SKIN BELOW THE LOWER EYELID

MENTAL N. BLOCK
MENTAL FORAMEN
DISCOLORATION OF SKIN OVER THE MENTAL FORAMEN OR SWELLING IN THE MUCOBUCCAL FOLD IN REGION OF MENTAL FORAMEN
PSA N BLOCK
SOFT TISSUE IN MUCOBUCCAL FOLD AS FAR AS POSSIBLE AS DISTALLY AS CAN BE TOLERATED BY PATIENT
COLORLESS SWELLING APPEAR ON SIDE OF FACE (USUALLY A FEW MINUTES AFTER THE INJEVTION IS COMPLETED)→DAYS INFERIOR AND ANTERIOR TOWARD THE LOWER ANT. REGION OF CHEEK

IN PSA HEMATOMA EARLIER IN PTERYGOID VENOUS PLEXUS
ACCORDING TO SICHER –PSA ARTERY

OF SORENESS DEVELOPS –ADVISE THE PATIENT TO TAKE ANALGESIC
DO ON APPLY HEAT OVER FOR AT LEAST 4-6 HOUR(VASODILATION-INCREASES IN SIZE)
HEAT APPLIED ON NEXT DAY-ACTS AS A)ANALGESIC AND B)    VASODILATORè↑RATE AT WHICH BLOOD ELEMENTS ARE RESORBED
IN FORM OF WARM MOIST TOWELS TO THE AFFECTED AREA FOR 20 MIN EVERY HOUR
RESOLVE S WITHIN 7-14 DAYS.


5)FAILURE TO OBTAIN ANESTHESIA

CAUSES
A)OPERATOR DEPENDENT
i)LA AGENT(TYPE,DOSE)
ii)IMPROPER SURGICAL TECH.
iii)INJ OF WRONG SOLN.
iv)I.V
v_I.M

B)PATIENT DEPENDENT
i)ANATOMICAL-ADDITIONAL INNERVATION
ii)PSYCHOLOGICAL –UNCOOPRATIVE,MOVEMENT
iii)PATHOLOGICAL-INFECTION

ADDITIONAL INNERVATION
CUTANEOUS COLLI NERVE’ (CERVICAL CUTANEOUS NERVE)-(A BRANCH OF 3RD CERVICAL NERVE)-ENTERS A SMALL FORAMEN ON LINGUAL ASPECT OD RAMUS AND SUPPLIES INNERVATION TO MANDIBULAR TEETH.
IN CASE OF FAILURE IN OBTAINING OPERATIVE ANESTHESIA AFTER A MANDIBULAR INJ. ,A SUPPLEMENTAL INJ.CAN BE GIVEN TO CERVICAL CUTANEOUS NERVE.THIS IS DONE BY INSERTING THE NEEDLE LINGUALLY BETWEEN 2 BICUSPID TEETH,AT THE REFLECTION OF MUCOUS MEMBRANE AND DIRECTING IT POSTERIORLY,ABOUT HALF OF THE NEEDLE IS INSERTED AND ABOUT 0.5ML OF SOLN. IS INJECTED.

4)POST INJECTION HERPETIC LESIONS

CAUSE
  • REACTIVATION OF DORMANT HERPES VIRUS
  • H/O RECUURENT HERPES LABIALIS
  • IN TERMINAL BRANCHES OF TRIGERMINAL NERVE

PREVENTION-DELAY SURGICAL INTERVENTION IN THE ACTIVE STAGE

MANAGEMENT-ANTIVIRAL DRUGS


C)COMPLICATIONS ARISING FROM BOTH

CAUSES
PREVENTION
MANAGEMENT

1)PAIN ON INSERTION
-CARELESS TECH.
-BLUNT NEEDLE
-RAPID INSERTION OF LA SOLN. CAN CAUSE TISUE DAMAGE
-HIGH TEMP. OF SOLN.
-PROPER TECH.
-SHARP NEEDLE-INSERT LA SLOWLY
-USE STERILE LA SOLN.
-USE TOPICAL LA B4
-SOLN. AT ROOM TEMP.
NOT REQUIRED
2)BURNING SENSATION
-RAPID INJ.
-CONTAMINATED NEEDLE CARTRIDGE
-HIGH TEMP. LA SOLN.
ALTERED PH OF SOLN. (PH PLAIN-5 APP,WITH VASOCONSTRICTOR-3 APP)

-SLOW INJ.
-SOLN. AT ROOM TEMP.
NOT REQUIRED
3)INFECTION
-CONTAMINATION OF NEEDLE
-IMPROPER PREP. OF SITE
-NEEDLE PASSING THROUGH AN AREA OF INFECTION
-LA SOLN DEPOSITED UNDER PRESSURE ,AS IN PDL INJ.→TRANSPORT BACTERIA
-PROPER PREP. OF SITE PRIOR TO PENETRATION
-CAREFUL HANDLING OF NEEDLES (AVOID TOUCHING NON-STERILE SURFACE)
-ANALGESICS
-ANTIBIOTICS
-PHYSIOTHERAPY
-MUSCLE RELAXANTS
4)EDEMA
-TRUAMA
-INFECTION
-ALLERGY
-HEMORRHAGE
-INJ OF IRRITATING SOLN.
-PREOP ASSESMENT
-CAREFUL HANDLING OF LA ARMAMENTARIUM
-ATRAUMATIC TECH.
-FIND OUT CAUSE
-ALLERGY-(A,B,C,D)
5)TISSUE BLANCHING
-TRAUMA TO BLOOD VESSEL BY NEEDLE
-I.V. ADMINISTRATION
-USE ASPIRATION TECH.
-AVOID INTRAARTERIAL ADMINISTRATION
-TRANSIENT PHENOMENON
-NO T/T REQUIRED


6)TRISMUS

CAUSES

PRIMARY CAUSE-TRAUMA TO MUSCLE ,BLOOD VESSELS IN INFRATEMPORAL FOSSA

SECONDARY CAUSES-
#INJECTION OF LA CONTAINING IRRITATING SOLN.(ALCOHOL,COLD STERILISING SOLN.)
#LA HAVE MILD MYOTOXIC PROPERTIES
(AIDS TO PROGRESSIVE NECROSIS OF EXPOSED MUSCLE FIBRES)
# HEMATOMA –(LEADS TO IRITATION OF MUSCLE FIBRES
# LOW GRADE INFECTION
# EXCESSIVE DEPOSITION OF LA-DISTENSION OF TISSUES-POST INJ TRISMUS
#THE BARB OCCURRED WHEN THE NEEDLE COME INTO CONTACT WITH THE MEDIAL ASPECT OF THR MANDIBULAR RAMUS,WITHDRAWL OF THE NEEDLE FROM TISSUE INCREASED THE LIKELIHOOD OF INVOLVEMENT OF THE LINGUAL OR IANB AND DEVELOPMENT OF TRISMUS

PROBLEMS
AVG. INTERINCISAL OPENING IN ACSES OF TRISMUS IS 13.7MM

IN CHRONIC HYPOMOBILTY-
  • IF T/T NOT GIVEN
  • SECONDARY TO ORGANISATION OF HEMATOMA WITH SUBSEQUENT FIBROSIS AND SCAR CONTRACTURE
  • INFECTION –INCRESED PAIN-INCRASED TISSUE REACTION(IRRITATION AND SCARRING).

PREVENTION

Ø  USE SHARP,STERILE,DISPOSABLE NEEDLE
Ø  USE ASEPTIC TECH.
Ø  ATRAUMATIC TECH.
Ø  AVOID MULTIPLE PENETRATION
Ø  USE MINM EFFECTIVE VOL. OF LA


MANAGEMENT

1)HEAT THERAPY-HOT MOIST TOWELS TO AFFECTED AREA FOR 20 MINS EVERY HOUR

2)WARM SALINE RINSE-HELD IN THE MOUTH ON THE INVOLVED SITE AND SPIT OUT

3)ANALGESICS ASPIRIN(325MG)

4)MUSCLE RELAXANTS-
CHLOROXAZONE (250 mg IN 2 TO 3 DIVIDED DOSE)
OR DIAZEPAM (5-10 mg BID)
OR MEMEPROBAMATE(1.2g IN 3-4 DIVIDED DOSES)

5)PHYSIOTHERAPY-OPENING AND CLOSING THE MOUTH ,AS WELL AS LATERAL EXCURSIONS OF THE MANDIBLE FOR 5 MINS EVERY 3 TO 4  HOURS.

6)CHEWING GUMS (SUGARLESS)-TO PROVIDE LATERAL MOVEMENT OF TMJ
7)ANTIBIOTICS

AVOID FURTHER DENTAL T/T IN INVOLVED REGION UNTIL SYMPTOMS RESOLVE AND PATIENT IS COMFORTABLE.

IF DENTAL CARE HAS TO BE CONTINUED –THAN ALTERNATE METHOD OR TECH. FOR ACHIEVING LA MAY BE EMPLOYED.
THE AKINSI MANDIBULAR N. BLOCK PROVIDES RELIEF FORM THA MOLAR DYSFUNCTION AND ALLOWS THE PATIENT TO OPNE THE MOUTH AND PERMITS ADMINSTARTION OF APPROPRIATE ADDITIONAL INJ. IF REQUIRED.
COMPELTE RESOLUTION OD POST INJ. TRISMUS TAKES APPROXIMATELT 6 WEKS ,WITH A RANGE OF 4 TO 20 WEEKS.

7)NEUROLOGICAL SYMPTOMS

A)VISUAL DISTURBANCES
i)SQUINT
ii)DIPLOPIA
iii)TRANSIENT AMAUROSIS
iv)PERAMNENT BLINDNESS

i)DIPOPIA OR DOUBLE VISION
v  LA SOLN. INFILTRATING INTO THE ORBIT TO ANESTHETIC THE EXTRINSIC OCULAR MUSLCES OF THE YES.
v  INTAARTERIAL INJ.-UNCOMMON VASCULAR PATTERNS-(ORBIT IS SUPPLIED EITHER WHOLLY OR PARTLY BY MIDDLE MENINGEAL ARTERY.)
v  NO MANAGEMENT REQUIRED (RESOLVES WITHIN 3 HOURS,OR WHEN EFECT ENDS)

ii)TRANSIENT SQUINT AND DOUBLE VISION
v  PARALYSIS OF EXTRINSIC MUSCLES
LA DIFFUSED INTO ORBIT FROM PTERYPALATINE GANGLION AND INFRATEMPORAL FOSSA VIA INFRAORBTAL FISSURE,EFFECTING OCCULOMOTOR,TROCHLEAR,ABDUCENS NERVE.

v  NO TREATMENT REQUIRED









CAUSES
PREVENTION
MANAGEMENT
FACIAL NERVE PARALYSIS

DIRECTLY LA DEPOSITION IN VICINITY OF 7TH CRANIAL NERVE
1)INFRAORBITAL N. BLOCK
2)PARAPERIOSTEAL OF MAXILLARY CANINE
INDIRECTLY-INTO DEEP LOBE OF PAROTID GLAND IN IANB

FOLLOW STANDARD PROTOCOL
EXPLAIN, REASSURE PATIENT
-UNILATERAL LOSS OF MOTOR FUNCTION-TRANSIENT
-EYE DRESSING GIVEN
-CONTACT LENSES SHOULD BE REMOVED
8)PERSISTENT PARATHESIA OR ANAESTHESIA
-INJECTING CONTAMINATED LA SOLUNTION
-TRAUMA TO N. SHEATH
-HEMORRAHGE AROUND N.
-FOLLOW STANDARD PROTOCAL
-CAREFUL SURGICAL TECH.
-PROPER HANDLING OF CARTRIDGE
-REASSURE THE PATIENT
- VIT B1,B6,B12
-IF DOES NOT RESOLVE THAN REFER FOR SURGERY
9)PERSISTENT PROLONGED PAIN
-POOR SURGICAL TECH.(IN SUPRAPERIOSTEAL TEARING VOL.)
-NEEDLE TIP BARBS
-ISCHEMIC NECROSIS
-MULTIPLE PENETRATIONS
-GOOD SURGICAL TECH.
-AVOID NEEDLE WITH BARBS
-USE VASOCONSTRICTORS WITH MAXIMUN DILUTION
-AVOID MULTIPLE PENETRATION
-SYMPTOMATIC


SYSTEMIC COMPLICATIONS OF LA

CAUSES OF ADVERS EDRUG REACTION

TOXICITY CAUSED BY DIRECT EXTENSION OF THE USUAL PHARMACOLOGICAL EFFECTS OF DRUGS-
1.SIDE EFFECTS
2.OVERDOSE
3.LOCAL TOXIC EFFECTS

TOXICITY CAUSED BY ALTERATION IN RECIPIENT OF THE DRUG
1.A DISEASE PROCESS(HEPATIC DYSFUNCTION,CHF,RENAL DYSFUNCTION)
2.EMOTIONAL DISTURBANCES
3.GENETIC ABBERATIONS(ATYPICAL PLASMA CHOLINESTERASE,MALIGNANT HYPERTHERMIA)

TOXICITY CAUSED BY ALLERGIC RESPONSES TO THE DRUGS

OVERDOSE
A DRUG OVERDOSE REACTIONS HAS BEEN DEFINED AS THOSE CLINICAL SIGNS AND SYMPTOMS THAT RESULT FROM AN OVERLY HIGH BLOOD LEVEL OF A DRUG IN VARIOUS TARGET ORGANS AND TISSUES

PREDISPOSING FACTOR
PATIENT FACTORS,DRUG FACTORS

PATIENT FACTOR
DRUG FACTOR
AGE
WEIGHT
OTHER DRUGS
SEX
PRESENCE OF DISEASE
GENETICS
MENTAL ATTITUDE AND ENVIRONMENT
VASOACTIVITY
CONC.
DOSE
ROUTE OF ADMINISTRATION
RATE OF INJ.
VASCULARITY OF INJ SITE
PRESENCE OF VASOCONSTRICTOR


CLINICAL  MANIFESTAIOTNS OF OVERDOSE

MINIMAL TO MODERATE OVERDOSE LEVELS
SIGNS
SYMPTOMS

q  TALKATIVENESS
q  APPREHENSION
q  EXCITABILITY
q  SLURRRED SPEECH
q  EUPHORIA
q  DYSARTHIA
q  NYSTAGMUS
q  VOMITTING
q  DISORIENTATION
q  LOSS OF RESPONSE TO PAINFUL STIMULI
q  ↑BP
q  ↑HR
q  ↑RR
q  LIGHTHEADENESS AND DIZZINESS
q  RESTLESSNESS
q  NERVOUSNESS
q  NUMBNESS
q  SENSATION
q  METALLIC TASTE
q  VISUAL DISTURBANCES
q  AUDITORY DISTURBANCES
q  LOSS OF CONSCIOUNESS
q  DROWSINESS AND DISORIENTATION



MODERATE TO HIGH OVERDOSE LEVELS
L  SEIZURE
L  CNS DEPRESSION
L  ↓BP
L  ↓HR
L  ↓RR

LIDOCAINE LEVEL
CVS

1.8-5.0 ug/ML
ANTIDYSRRTHMIC ACTIONS
5.0-10.0
MYOCARDIAL DEPRESSION
10.0PLUS
MASSIVE PERIPHERAL VASODILATION,MYOCARDIAL DEPRESSION
CARDIAC ARREST


CNS
0.5-4
ANTICONVULSANT ACTION
4.5-7
CNS DEPRESSION,EXCITATION
7.5-10.0
CNS DEPRESSION ,SEIZURE
10.0 PLUS
GENERALIZED CNS DEPRESSION



CVS EFFECTS

LA (VASODILATOR)
PERIPHERAL RESISTANCE
↓BP(BP=PR*CO)

FURTHER IN LA CONC.

AFFECT N. CONDUCTION OF HEART
MYOCARDIAL CONTRACTILITY
C.O.(CO=HR*SV)

HEART’S NEURONAL CONDUCTION SYS. IS INHIBITED OR COMPLETELY BLOCKED BY LA.
AT TOXIC LEVELS,DEPRESSION OF INTRACARDIAC N. CONDUCTION CAN RESULT IN ATRIOVENTRCULAR DISSOCIATION,VENTRICULAR RHYTHM ,VENTRICULAR FIBRILLATION AND ULTIMATELY CARDIAC ARREST.

CNS EFFECTS

THE CONDUCTION OF INHIBITORY NEURONS ID USUALLY BLOCKED BY LA AGENTS AS THEY REACH TOXIC LEVELS-RESULTING IN UNMODIFIED ACTION OF FACILITATORY NEURONS(IE,CONVULSIVE-LIKE MOVT.)AS THE DOSE INCREASES,FACILITATORY NEURONS ARE ALSO BLOCKED RESULTING IN CESSATION OF FUNCTION.
CERTAIN AMIDE TYPE AGENTS(IE LIDOCAINE)-EFFECT PRIMARILY FACILATORY NEURONS,HENCE DEPRESSION IS SEEN RATHER THAN EXCITATION.


MANAGEMENT

1)MILD OVERDOSE
RETENTION OF CONCIOUSNESS,TALKATIVENESS,AGITATION,
↑HR,↑BP. ↑RR(5-10 MIN)→←

P→A→B→C→D

DEFINITIVE CARE
i)REASSURE THE PATIENT
ii)ADMINISTER OXYGEN VIA NASAL CANULA TO PREVENT ACIDOSIS
iii)MONITOR AND RECORD VITAL SIGNS
iv)ESTABLISH i.v. INFUSION
v)USE OF ANTICONVULSANTS –NOT USUALLY INDICATED
       DIAZEPAM-5mg.MIN i.v.
        MIDAZOLAM-1mg/MIN

2)SEVERE OVERDOSE
UNCONSCIOUSNESS WITH OR W/O CONVULSIONS
RAPID ONSET(WITHIN 1 MINUTE)

i)PROTECT PATIENTS ARMS,LEGS AND HEAD
LOOSEN TIGHT CLOTHES
ii)IMMEDIATELY SUMMON EMERGENCY MEDICAL ASSISTENCE.
iii)CONTINUE BLS
iv)ADMINISTER ANTICONVULSANT
    DIAZEPAM –i.v -5mg/min
IF VENEPUNCTURE NOT FEASIBLE
     MIDAZOLAM-im -1mg
IF HYPOTENSION PERSISTS(30 MINS)-VASOPRESSOR
     (PHENYNEPHRINE OR METHAOXAMINE)IM

EPINEPHRINE OVERDOSE

CLINICAL MANIFESTATIONS
SIGNS-↑BP. ↑HR,CARDIAC DYSRTHYMIAS

SYMPTOMS-FEAR,ANXIETY,THROBBING HEADACHE,PERSPIRATION,WEAKNESS,PALLOR,RESP. DIFFICULTY,PALPITATION

EPINEPHRINE
mg/ml
Mg/CARTRIDGE
MAX NO. OF CARTRIDGES
1:50,000
0.02
0.036
5(H),1(C)
1:100,000
0.01
0.018
10(H),2©
1:200,000
0.005
0.009
20(H),4©


MANAGEMENT
P→A→B→C→D
P-SEMISITIING OR ERECT POSITION( ↓CEREBRAL BP)

i)REAASURE THE PATIENT
ii)MONITOR VITAL SIGNS
iii)OXYGEN ADMINISTERE IF NECESSARY( C/I IN HYPERVENTILATION)
iv)RECOVERY


ALLERGY

ALLERGY IS A HYPERSINSITIVE STATE,ACQUIRED THROUGH EXPOSURE TO A PARTICULAR ALLERGEN,REEXPOSURE TO WHICH PRODUCE HEIGHTENED CAPACITY OT REACTION.

PREDISPOSING FACTORS
z  METHLYPARABEN
z  SODIUM BISULPHITE ALLERGY
z  EPINEHRINE
z  LATEX ALLERGY
z  TOPICAL ANESTHETIC ALLERGY

PREVENTION-PROPER HISTORY

ALLERGY TESTING
0.1ML OF EACH(INTRAVENOUS)
  0.9%NACL

  1% OR 2% LIODCAINE,
  3%MEPIVACAINE
  4%PRILOCAINE(W/O METHYL PARABEN,BISULPHITE,VASOPRESSORS.

INTRAORAL CHALLENGE TEST
0.9 ML OF LA SOLN. SUPRAPERIOSTEAL INFILTRATION ATRAUMATIC(BUT W/O TOPICAL LA)ABOVE A MAXILLARY RIGHT OR LEFT PREMOLAR OR ANT. TOOTH.

DENTAL MANAGEMENT IN CASE OF PRESENCE OF LA ALLERGY:
Í NO T/T OF AN INVASIVE NATURE CARRIED OUT
Í IF EMERGENCY –THEN UNDER GENERAL ANESTHESIA
Í IF GA NOT AVAILABLE –HISTAMINE BLOCKER
DIPPHENHYDRAMINE HCL IN 1 % SOLN. WITH 1:100,000 EPINEPHRINE(30 MIN OF PULPAL ANESTHESIA)
Í NITORUS OXIDE
Í ALTERNATIVES-ELECRONIC DENTAL ANESTHESIA


CLINICAL MANIFESTATIONS OF ALLERGY

DERMATOLOGICAL REACTIONS-
URTICARIA-WHEAL
ANGIOEDEMA-LOCALISED SWELLING INVOLVING FACE,HANDS,FEET,GENITILIA,LIPS,TONGUE.

RESPIRATORY REACTIONS-
BRONNCHOSPASM
RESP. DISTRESS
DYSPNOEA,WHEEZING,FLUSHING,CYANOSIS,PERSPIRATION,TACHYCARDIA,INCREASED ANXIETY,LARYNGEAL EDEMA

GENERALISED ANAPHYLAXIS
SKIN REACTION-PRURITIS,ERYTHEMA,URTICARIA,CONJUCTIVITIS,RHINITIS
GIT DISTURBANCE
RESP STMPTOMS-WHEEZING,DYSPNOEA
CVS-PALLOR,TACHYCARDIA,HYPOTENSION,CARDIAC DYSARRTHYMIA,UNCONCIOUSNESS,CARDIAC ARREST


MANAGEMENT

P→A→B→C→D
i)ADMINISTER EPINEPHRINE 0.3mg IM/SC OR
 HISTAMINE BLOCKER-50mg DIPHENHYDRAMINE OR
10 mg CHLORPHENIRAMINE
ii)MEDICAL CONSULTATION FROM PHYSICIAN
iii)OBSERVE THE PATIENT (60MIN)
iv)PRESCRIBE ORAL HISTAMINE BLOCKER
    50 mg CAP-TDS FOR 3-4 DAYS


BRONCHSPASM
P→A→B→C→D

i)TERMINATE T/T
ii)ADMINISTER OXYGEN (5-6 L/MIN)
iii)ADMINISTER EPINEPHRINE 0.3 mg IM/SC
iv)ADMINISTER HISTAMINE BLOCKER TO MINIMIZE RELAPSE
HISTAMINE BLOCKER-50mg DIPHENHYDRAMINE OR
10 mg CHLORPHENIRAMINE
 v)MEDICAL CONSULTATION

LARYNGEAL ODEMA
P→A→B→C→D
i)ADMINISTER EPINEPHRINE 0.3 mg IM/SC
ii)EMERGENCY MEDICAL SERVICE
iii)MAINTAIN AIRWAY
iv)ADDITIONAL DRUGS
HISTAMINE BLOCKER
-50mg DIPHENHYDRAMINE OR
10 mg CHLORPHENIRAMINE
CORTICOSTEROID-
  100mg HYDROCORTICOSONE IM/IV

GENERALIZED ANAPHYLAXIS
P→A→B→C→D
i)                    EMERGENCY MEDICAL SERVICE
ii)                  EPINEPHRINE (0.3ML OF 1:1000) IM/IV
iii)                OXYGEN AND VITAL SIGNS
iv)                IF DOES NOT IMPROVE SECOND DOSE OF EPINEPHRINE IN 10 MIN
v)               ADDITIONAL DRUGS
                 HISTAMINE BLOCKER
                       -50mg DIPHENHYDRAMINE OR
                          10 mg CHLORPHENIRAMINE
                CORTICOSTEROID-
                        100mg HYDROCORTICOSONE IM/IV